Wednesday 14 May 2014

Unique Features of Mammogram Tube ans X - Ray Spectrum

INTRODUCTION
            Mammography is one of the most demanding radiologic techniques.  It requires an excellent spatial resolution to allow visibility of microcalcifications and good contrast sensitivity to allow detection of breast tumors.   It is difficult to visualize very small physical changes in breasts with general x-ray imaging.  That is why mammography equipment was designed differently from general x-ray.  
UNIQES FEATURES OF MAMMOGRAM TUBE
            Mammography equipment consists of two major components.  They are an x-ray tube and an image receptor.  The x-ray beam originates at the x-ray tube and transmitted through the breast.  A film contained in the image receptor to record the images from x-ray distribution that passed through the breast tissue.




Image receptor
Figure 1. Mammogram Equipment. Reprinted from Screen-film Mammography Equipment Unit 3, by B.A. Barnes & X. Ho, n.d., Retrieved from www.santarosa.edu/.../Unit%203%20-%20Mammography. Reprinted with permission.
           
Features of mammogram x-ray tube that are unique compare to general x-ray tube include x-ray tube anode, target materials, filament design, filter, focal spots, source-to-image distance, and object to image receptor distance.
            Most x-ray tubes use tungsten as the anode material, however mammography equipment uses molybdenum and in some designs, it uses a dual material anode with an additional rhodium track.  Molybdenum and rhodium are used because they produce a characteristic radiation spectrum that is close to optimum for breast imaging (Sprawls, 1995).     
            To reduce unnecessary exposure to the patient, most x-ray machines use aluminum to filter the x-ray beam.  Sprawls (1995) mentioned that mammography uses filters that work on different principle and also used to enhanced contrast sensitivity.  Same as in the anode, molybdenum is the standard filter material.  Some systems allow the operator to select either the molybdenum or rhodium filter to optimize the spectrum for specific breast conditions (Sprawls, 1995).
            There is also exit window filtration (Barnes & Ho, n.d.).  Instead of glass, beryllium is used in dedicated mammography tube housing.  Noted that glass act as a filter when dealing with this soft end of the x-ray spectrum, and it filters out photons that would not provide contrast (Barnes & Ho, n.d.).      
            Mammographic x-ray tubes typically have dual filaments in a focusing cups that produces 0.3 and 0.1 mm nominal focal spot sizes (Barnes & Ho, n.d.).  Meaning x-ray tube for mammography has two selectable focal spots.  The spots are smaller compared to other x-ray procedures because mammogram requires for minimal blurring and good visibility of detail to see the small calcifications.  The smaller of the two spots is generally used for the magnification technique (Sprawls, 1995).  Magnification views use a small magnification table which brings the breast closer to the x-ray source and further away from film plate.  This allows the acquisition of zoomed in images of the region of interest (special mammography views, 2008).   
            Other unique component in mammography tube which is source-to-image distance (SID).  SID is the entire distance of the x-ray beam from the focal spot to the image receptor (Barnes & Ho, n.d.).  The greater the distance the less geometric blurs occur.  This affects the focal spot size which affects the size of the objects being imaged.  The larger the SID the larger the field size.  With larger distance of the source to the image, more beam will be needed to penetrate which then can increased the heel effect (Barnes & Ho, n.d.).
            Other feature is object to image receptor distance (Barnes & Ho, n.d.).  It is the distance of the object (the breast) to the image receptor.  Increase of the object to image receptor distance will increase magnification of an area of breast tissue.  It will increase the resolution and contrast of the breast image (Barnes & Ho, n.d.).
 Figure 2. Principle of Mammogram Tube. Reprinted from Mammography Physics and Technology for Effective Clinical Imaging, by P. Sprawls, 1995, Retrieved from http://www.sprawls.org/resources/MAMMO/mammo02.jpg. Copyright 1995 by Sprawls Educational Foundation. Reprinted with permission.








THE X-RAY SPECTRUM
              The x-ray spectrum depends on the combination of three factors.  First factor is the x-ray tube anode material (molybdenum or rhodium), second is material used for x-ray beam filtration (molybdenum or rhodium), and third is the kV which ranging from 24 kV to 32 kV (Sprawls, 1995). 
            As for x-ray tube anode, most mammogram unit uses molybdenum anodes.  However, in some systems have a dual-track anode that allows radiographer or AEC system to select between molybdenum and   rhodium.
            For x-ray beam filtration, the material used is also molybdenum but in some systems they have an alternative rhodium filter that can be selected.  According to Sprawls (1995) the molybdenum filter only should be used with the molybdenum anode.  However, the rhodium filter can be used in combination with both the molybdenum and rhodium anodes.
Figure 3. Factors Affecting the X-ray Spectrum. Reprinted from Mammography Physics and Technology for Effective Clinical Imaging, by P. Sprawls, 1995, Retrieved from http://www.sprawls.org/resources/MAMMO/mammo18.jpg. Copyright 1995 by Sprawls Educational Foundation. Reprinted with permission.

                         
            In physics, there are two types of x-ray radiation produced when electrons hit the x-ray tube anode.  They are bremsstrahlung and characteristic.  Bremsstrahlung is in the form of a broad continuous photon energy spectrum with a maximum energy determined by the selected kV value (Sprawls, 1995).  Characteristic radiation is produced under certain conditions and is confined to just a few photon energies (Sprawls, 1995).      
            The photon energies of the characteristic radiation are determined by the atomic characteristics of the anode material which varies with the atomic number (Z) of the material.  For mammography, molybdenum and rhodium are materials that produce characteristic x-ray radiation that is near the optimum energy which is why they are used for the anodes (Sprawls, 1995).
            In mammography, the filters used are based on the ‘k-edge’ principle and it attenuates the radiation above the k-edge energy of the specific material (Sprawls, 1995).
Figure 4. K-edge Principle. Reprinted from Mammography Physics and Technology for Effective Clinical Imaging, by P. Sprawls, 1995, Retrieved from http://www.sprawls.org/resources/MAMMO/mammo28.jpg. Copyright 1995 by Sprawls Educational Foundation. Reprinted with permission.

           


            Sprawls (1995) noted that with an atomic number of 42, molybdenum has a k-shell binding energy and its k-edge at energy of 20 keV and rhodium, with an atomic number of 45 also has a k-shell binding energy and its k-edge at energy of 23.22 keV.  When molybdenum filter is selected, it attenuates and blocks much of the bremsstrahlung spectrum above the energy of 20 keV and gives results in the spectrum that is most often used in mammography which is ‘moly/moly’ anode/filter combination (Sprawls, 1995).
Figure 5. The Moly/Moly Spectrum. Reprinted from Mammography Physics and Technology for Effective Clinical Imaging, by P. Sprawls, 1995, Retrieved from http://www.sprawls.org/resources/MAMMO/molymoly.jpg. Copyright 1995 by Sprawls Educational Foundation. Reprinted with permission.

           






            The k edge boundary is shifted to a higher energy with the rhodium filter.  So the portion of the bremsstrahlung between 20 keV and 23.22 keV is added to the x-ray beam.  This makes the beam more penetrating which provides some advantage when taken image of larger or denser breast (Sprawls, 1995).
Figure 6. The Moly/Rhodium Spectrum. Reprinted from Mammography Physics and Technology for Effective Clinical Imaging, by P. Sprawls, 1995, Retrieved from http://www.sprawls.org/resources/MAMMO/molyrho.jpg. Copyright 1995 by Sprawls Educational Foundation. Reprinted with permission.

   
           







            Another anode material is rhodium.  Rhodium can be selected to produce a more penetrating x-ray beam.  Rhodium’s atomic number (Z) is 45 and has principal characteristic radiation at energy of 20.3 keV with a less intense emission at 22.7 keV.  Compare to molybdenum which atomic number (Z) is 42 and principal characteristic energy of 17.6 keV with less intense peak at 19.7 keV (Sprawls, 1995).
            The rhodium filter, with a k-edge cut off at 23.22 keV, is always used with the rhodium anode.  The molybdenum filter cannot be used with rhodium anode because its k-edge cut off from 20 keV upward would attenuate the rhodium 20.3 keV and 22.7 keV radiations (Sprawls, 1995).
Figure 7. The Rhodium/Rhodium Spectrum. Reprinted from Mammography Physics and Technology for Effective Clinical Imaging, by P. Sprawls, 1995, Retrieved from http://www.sprawls.org/resources/MAMMO/rhorho.jpg. Copyright 1995 by Sprawls Educational Foundation. Reprinted with permission.


           



            Third factor that affect the x-ray spectrum is kV.  Increasing the kV has two effects on the x-ray beam.  First, it increases the efficiency and output for a specific mAs value and second it shifts the photon energy spectrum upward so that the beam becomes more penetrating (Sprawls, 1995).  Penetrating beam reduce contrast sensitivity and it is necessary for dense breast.  Therefore compressed breast thickness is the principal factor that determines the optimum kV (Sprawls, 1995).
Figure 8. KV Selection for Different Breast Thickness. Reprinted from Mammography Physics and Technology for Effective Clinical Imaging, by P. Sprawls, 1995, Retrieved from http://www.sprawls.org/resources/MAMMO/mammo32.jpg. Copyright 1995 by Sprawls Educational Foundation. Reprinted with permission.



DISCUSSION
            According to Sprawls (1995) the photon energy spectrum of the x-ray beam is one of the most critical factors in optimizing a procedure with respect to contrast sensitivity and radiation dose.  Although many said that anode materials used in mammogram can only be molybdenum and rhodium, today many researchers do the study on tungsten as an anode material for mammogram tube to see whether it still can produce good contrast and low radiation dose. 
            Between all of the anode materials used in mammography tube, which are molybdenum, rhodium, and specialized tungsten, many researchers agree that molybdenum is the best material to be used because it allows production of low energy spectrums of radiation and only need low kVp which is 26 to 30 kVp (Barnes & Ho, n.d.). 
            However, recently there is study done using tungsten as an anode material with rhodium in mammography and according to researchers, if the molybdenum x-ray tube digital mammography demonstrated a 30 percent reduction in dose, the introduction of tungsten x-ray tubes with digital mammography allows even greater reduction in radiation exposure, without affecting image quality (Smith, Chen, & Semine, 2005).
            Another study done from Dance, Klang, and Sanborg (2000) to compare performance of mammographic x-ray systems that use different anode/filter combinations for screen film and digital imaging.  For screen film mammography, result for thicker breasts shows 20 percent improvement in contrast can be achieved but without reduce radiation dose using molybdenum/rhodium or rhodium/rhodium,  Whereas more than 50 percent of dose saving can be attained but no improvement in contrast using tungsten/rhodium or rhodium/aluminum spectra.  As in digital mammography, Dance et al. (2000) mentioned that molybdenum/molybdenum spectrum delivers the lowest dose for a two centimeter breast, but gives the highest dose for thicker breasts.  However tungsten/rhodium or rhodium/aluminum spectra provide the lowest doses at greater thickness.  Researchers concluded that from this study, molybdenum/molybdenum is the spectrum of choice for all but not for thicker or most glandular breasts.

CONCLUSION
            The most important part of dedicated equipment in mammography is the x-ray tube.  The tube is designed and constructed uniquely and specifically for imaging the soft tissue of the breast.  The x-ray machines used for mammograms today designed to produce lower energy x-rays but improves in image quality and less radiation.   






REFERENCES
Barnes, B.A., (n.d.). Screen-Film Mammography Equipment Unit 3. Retrieved April 27, 2013,     from www.santarosa.edu/
Dance, D.R., Klang, A.T., Sandborg, M., Skinner, C.L., Smith, A.C., & Carlsson, G.A. (2000).    Influence of anode/filter material and tube potential on contrast, signal-to-noise ratio and           average absorbed dose in mammography. The British Journal of Radiology, 73 (2000),            1056-1067. Retrieved from bjr.birjournals.org/content/73/874/1056.full.pdf
Smith, A., Chen, B., & Semine, A. (2005). Minimizing Dose in Digital Mammography.     Retrieved May 02, 2013, from www.hologic.com.data/WP_00005_tungsten
Sprawls, P. (1995). Mammography Physics and Technology for Effective Clinical Imaging.          Retrieved April 28, 2013, from www.sprawls.org/resources/mammo/module.htm
Special Mammographic Views. (2008). Retrieved April 28, 2013, from             www.imaginis.com/mammography/special-mammography-views-spot-c
            



     
 


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